For Clinicians & Care Organizations

The behavioral layer of conservative osteoarthritis care is missing

Guidelines put exercise and self-management first-line β€” but patients who believe pain means damage don't engage with either. Rethink OA is a digital mindset program, tested in an education-controlled randomized trial, that changes what patients believe so they change what they do. Under 2 hours. Zero clinician time.

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Read the trial in npj Digital Medicine

You already tell patients to move. Here's why they don't.

Most patients with knee osteoarthritis arrive believing their joint is wearing out and that activity accelerates the damage. That belief drives fear of movement, activity avoidance, poor PT adherence, and the conviction that surgery is inevitable. A 15-minute visit can't undo it β€” and handouts don't either: in our trial, an attention-matched education program moved knowledge, but it was significantly less effective than Rethink OA at reducing fear of movement, building self-efficacy, and shifting surgical expectations.

Rethink OA is the structured behavioral layer that does that work between your visits β€” so the time you do have goes further.

 

Four modules. Under two hours. Zero clinician time.

A self-guided digital program β€” short films featuring Stanford experts and real patients, plus structured reflection β€” that patients complete on any device. It slots into existing pathways without workflow changes:

  • At diagnosis (primary care): give patients an evidence-based next step beyond 'stay active,' in the moment the diagnosis lands.
  • Alongside PT: reduce kinesiophobia before and between visits so home programs actually get done.
  • In orthopedic pathways: standardized expectation-setting for not-yet-surgical patients, and preparation for those proceeding.
  • In value-based contracts: a low-cost, population-scale intervention for the OA cohort driving MSK spend.

Rethink OA complements medical care, PT, and surgical pathways β€” it never replaces them.

Discuss how Rethink OA fits into your care pathway

Clinical Evidence

A randomized controlled trial with an education control β€” not a pre-post case series

Rethink OA was tested against both an attention-matched education program and a no-intervention control in 408 adults with symptomatic knee osteoarthritis, with outcomes at one-month follow-up. Responder rates below use published minimal clinically important differences (MCIDs) where available.

N = 408 completers 3-arm RCT, education-controlled Prospectively registered Β· NCT05698368 Published in npj Digital Medicine (Nature Portfolio) 86% completion No serious adverse events

Fear of movement

% achieving meaningful improvement (BFMSO)1

d = 0.68
Effect size
NNT β‰ˆ 3
vs. no program
59%
Rethink OA
50%
Education control
21%
No intervention

Physical activity

% gaining β‰₯26 PASE points2

+39 pts
Mean PASE gain
NNT β‰ˆ 6
vs. no program
52%
Rethink OA
49%
Education control
34%
No intervention

Perceived need for surgery

% improving β‰₯1 category (5-pt scale)3

d = 0.58
Effect size
NNT β‰ˆ 5
vs. no program
44%
Rethink OA
27%
Education control
22%
No intervention

Fear of movement, pain self-efficacy, osteoarthritis knowledge, and perceived need for surgery each improved significantly vs. both the education and no-intervention groups (P < 0.001). Physical activity improved significantly vs. no intervention (P = 0.001).

d = 0.78
Pain self-efficacy (+1.4 pts; P < 0.001 vs. both controls)
69%
improved in 4+ of 8 outcomes, vs. 39% untreated
28%
of surgery-likely patients no longer likely at one month, vs. 14% untreated4
0 hrs
of clinician time required β€” fully self-guided, <2 hours per patient

1Meaningful improvement = β‰₯0.33 avg-point reduction on BFMSO (β‰ˆ12% of scale range; no published MCID β€” threshold documented in our methods workbook). Rethink OA 59% vs. education 50% vs. no intervention 21%. 2β‰₯26 points on PASE, the trial's pre-specified clinically relevant threshold (no published PASE MCID). 3β‰₯1 full category on a 5-point Likert scale. 4Among patients rating themselves "likely/very likely" to need surgery at baseline (72% of the Rethink OA group). Perceived need for surgery is an attitude measure, not surgical utilization. Effect sizes (d) are within-group standardized changes, baseline to one-month follow-up, in the Rethink OA group; between-group significance is reported separately (P values), and responder bars compare all three arms directly. All outcomes self-reported at one-month follow-up. Boswell MA, et al. npj Digital Medicine 7, 285 (2024). doi:10.1038/s41746-024-01281-8.

Rethink OA Β· Value-Based Care

What could Rethink OA save your organization?

Savings estimates are modeled from our randomized clinical trial (npj Digital Medicine, 2024) and published health-economics literature. Adjust the inputs to match your population.

Your population

Tell us about the knee OA patients you manage.

$
5%

Baseline annual spend per patient

Typical non-surgical knee OA spend. Pre-filled from published cost data β€” edit to match your claims.

$
$
$
Adjust savings assumptions (pre-set to our Base Case)β–Ύ
25%
15%
15%
5%
$30
Estimated net annual savings
$3.4M
across 20,000 patients Β· after program costs
$170
net savings per patient / yr
2.8Γ—
return on every program dollar
$170K
net savings per 1,000 patients

Where the savings come from (per patient / yr)

Surgery deferral
$68
Specialist visits
$60
Injections
$50
Activity & activation
$30
Imaging
$23
Gross savings $230  βˆ’  program cost $60= $170 net
Break-even: one deferred knee replacement covers the program for 450 patients β€” just 2.2 deferred surgeries per 1,000 enrolled pays for everything.

Take these numbers with you

Generate a branded PDF report of this exact scenario β€” ready to save, print, or share with your finance and clinical teams.

Built to deploy wherever OA patients are managed

  • Value-based care organizations & medical groups: Deploy across your OA population; track engagement and outcomes. Priced to make the pilot decision easy.
  • Health plans: A supplemental benefit members actually finish: 86% completion, 4.8/5 would recommend.
  • Digital MSK & health platforms: License the validated mindset layer your engagement funnel is missing.
  • PT clinics & specialty practices: Refer patients directly today β€” or talk to us about clinic-level access for your caseload.Β 

Developed at Stanford. Tested like a therapeutic.

Β Rethink OA was built at Stanford University by a team spanning bioengineering, psychology, orthopedic surgery, and health behavior, with patients involved throughout the design process. It was evaluated in a prospectively registered, three-arm randomized controlled trial (NCT05698368) with an attention-matched education control, and published in npj Digital Medicine, a Nature Portfolio journal. Founder Melissa Boswell, PhD (Assistant Professor of Biomedical Engineering, Wake Forest University School of Medicine) is the first author of the trial.

Outcomes are self-reported at one-month follow-up; between-group pain change did not reach significance (P = 0.054). We publish our thresholds and share our data dictionary with partners β€” ask us for it.

Bring Rethink OA to Your Patients

Tell us about your organization, and we'll follow up within two business days β€” with the trial data, implementation options, and pilot pricing.

HSA and FSA Eligibility

Individual patients may be eligible for HSA/FSA reimbursement with an LMN

More Information on HSA and FSA